Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other alerts from your microenvironment and growing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic research have recognized recurrent mutations in genes regulating tumor mobile-microenvironment interactions, ... https://francesc689xwv0.worldblogged.com/profile