Whilst the secretion of glucocorticoids in reaction to stressful stimuli is really an adaptive reaction needed for an organism to respond appropriately to the stressor, persistent secretion could be harmful. The endocannabinoid system is implicated from the habituation from the hypothalamic-pituitary-adrenal axis (HPA axis) to repeated exposure to restraint worry. https://zanenwfls.sharebyblog.com/32332329/how-cannabis-strains-can-save-you-time-stress-and-money