If a guardian from the proband is known to have the pathogenic variant discovered inside the proband, the risk to your sibs of inheriting the pathogenic variant is 50%. Thanks to lowered penetrance, sibs who inherit the pathogenic variant may or may not produce aHUS (see Penetrance). The ACR 160kw https://ricardokquxc.bloggerchest.com/32351874/top-ahu-s-secrets