This refers to how an allosteric modulator affects signaling for a specific orthosteric agonist. Such as, an allosteric modulator may alter THC signaling, but not endogenous cannabinoid signaling. A vital potential endogenous detrimental allosteric modulator for CB1 is the steroid hormone, pregnenolone [40–42]. Some (although not all [43–45]) investigators have https://vehicleaccidentrights20706.yomoblog.com/39327626/5-tips-about-cannabis-you-can-use-today