See the Interactions area for more information. Also notify your Health care provider Should you have used clonidine transdermal patches (Catapres-TTS) and also have had an allergic reaction. Clonidine treats high blood pressure level by stimulating α2 receptors inside the brainstem, which decreases peripheral vascular resistance, reducing blood pressure. https://www.proleviate.com/post/the-new-pain-killer-conolidine