Topoisomerase II brings about transient double-strand breaks in the course of the twisting of 2 double-stranded DNA helices. Singleand double-stranded DNA breaks are actually documented after in vivo and in vitro treatment with doxorubicin of P388 leukaemia cells in mice[8]. Administer doxorubicin intravenously over three to ten minutes. Decrease the https://irvingg617zoz1.blgwiki.com/user